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life span | Nevada Senior Guide

Life Extension: The Modern Anti-Aging Movement – Are We Standing at the Threshold of Immortality?

July 17, 2016 by · Comments Off on Life Extension: The Modern Anti-Aging Movement – Are We Standing at the Threshold of Immortality?
Filed under: General 

Why is skincare the focus of longevity research? I guess a cell is a cell, and if you can crack the code for one human cell, it is only a matter of time to solving the puzzle with different types of cell – and skin is without doubt the most visible cells each of us have. And it’s our faces in particular we often judge ourselves and others by, and we are in turn quickly scrutinized, and often opinions reached in a fraction of a second. Our faces often show the most visible signs of aging, and for many in modern society age is by nature “bad” and young or looking young is the ideal. That is why billions and billions of dollars each year are poured by consumers into all sorts of treatments to minimize wrinkles, to push back the effects of gravity, and to turn back the hands of time. And with that much money to be spent by consumers, there are many manufacturers eager to find the next step in arresting Father Time – and at least detaining him until the next stagecoach arrives, where hopefully he can be encouraged to move on before too much damage can be done.

The Entire Issue Explained – In A Pair of Shoelaces

Some time ago a friend gave me a simple analogy that puts this entire issue in perspective. The science may not win a Nobel Prize, but it gave me the necessary ah-ha moment.

The double helix of the DNA strand – our most basic foundation for life – is held together at each end by things that act in the same way as the hard plastic bits on the end of shoelaces do – preventing the DNA from unraveling, and the individual chromosomes scattering across the floor like dropping a string of pearls down a marble staircase. These things are called telomeres.

Somewhere programmed into these tiny telomeres is the entire basis to how long the DNA stays intact – and by inference these are the keys to the length of life of the organism. Somewhere written into the telomere is a great musical score but like all musical scores it has a double bar somewhere to signify the end; but is it to be a minuet or a Wagnerian epic? But sure enough, when the time comes, and the telomeres blow the full time whistle, the DNA strand will unravel and die – and the circle of life begins again. Telomeres govern how often our skin cells are replaced; why a puppy and a child born on the same date may age exactly the same chronologically, but the puppy has become a geriatric before the child reaches puberty.

Telomeres, my friend explained, occasionally go on the fritz (that must have a very specific scientific meaning). One of the ways this occurs is they may forget their programming to release and unravel, and they just hang on, allowing the cells thus affected to multiply again and again without dying. In fact, when this occurs often they become very difficult to kill and to all intents and purposes once the telomeres act in this way, the cell – and those it propagates – are effectively immortal.

This condition has a name which we all know. Cancer.

But, what if we were able in some way to persuade the telomeres within a cancer to behave normally – would that not be the “magic bullet” cure for cancer? And the other side to that equation – if the telomeres in healthy cells could be persuaded to act as they do in a cancer – then is this the recipe for a healthy cell that does not die? Does the cure for cancer and immortality hang on just this one thread?

Whatever your views may be, the reality is that some of the world’s finest research scientists are working on that exact question and some would say it is only a matter of a decade or two before this is neither conjecture nor science fiction, but a reality to face up to. The changes that would take place in society even if life expectancy were to take a leap forward by say 10 or 20 years are enormous, but we should all be thinking that this is a distinct possibility.

From the dab of lanoline a generation ago to what I know hold in my hand as an anti aging skincare treatment is more than just a revolution – and I have no doubt in a few years I will be saying this cream will not just slow the aging process and reduce the visible signs of aging, making your face appear younger – but it will actually be younger.

But before that, let’s look back at how this whole engagement with life extension and anti-aging started. Mankind has always striven for longevity and mused about immortality – but the past 50 years has seen some dramatic steps in reality toward this goal.

Genesis

The thought of extending life has been on the mind of mankind for millennia. References to the search for ways to prolong life can be found as far back as the Epic of Gilgamesh.

Gilgamesh was reputedly the fifth king of the kingdom of Uruk, the modern-day Iraq, around 2500 BC. According to the Sumerian list of kings, he reigned for 126 years. The Torah or Old Testament records Methuselah as living over 900 years, with life spans measured in centuries apparently commonplace before the time of Noah.

Throughout the development of scientific thought from the Reformation onwards, scholars have applied themselves to solving this riddle and these endeavors continue today at the very leading edge of scientific progress.

Unraveling Secrets

As the secrets of our existence are unraveled in ever more minute detail, we are beginning to understand what it is that makes us grow from tiny babies into adults. We now know, for example, that cell functions slow down as the body ages and that production of certain substances required by the body to regenerate decrease or cease completely.

Skin, for instance, needs two substances to retain strength and firmness.
The production of these substances namely collagen (strength, tightness) and elastin (flexibility) decreases with age. The decreases in production together with other factors that include the threat of free radicals make the skin age and become wrinkly. Free radicals are essentially incomplete oxygen molecules causing destructive chain reactions within cells.

The same kind of thing happens in every cell, every tissue and organ around the human body. For example, people develop frown lines, crow’s feet and wrinkles. Nutrients are no longer absorbed easily and vital cell functions, hormones and other substances are produced at decreased rates resulting in the body aging.

A Brief History of the Life Extension Movement

Science has been looking for ways to slow down this process for centuries. The forming of life extension movements, however, did not really begin until around 1970.

➢ In this year, Denham Harman, the originator of the so-called ‘free radical theory of aging’, decided that an organization dedicated to the research and information sharing between scientists working in biogerontology (the field of science concerned with the biological aspects involved in the aging process) was needed. As a result, the American Aging Association was formed.

➢ In 1976, two futurists, Philip Gordon and Joel Kurtzman wrote a book on the research into extending the human lifespan. This popular volume was titled ‘No More Dying. The Conquest Of Aging And The Extension Of Human Life’.

➢ Kurtzman was then invited to speak at Florida’s House Select Committee (HSC) of Aging, which was chaired by Claude Pepper, an American politician and spokesman for the elderly. The aim of this talk was to discuss the impact on Social Security by life extension.

➢ In 1980, Saul Kent, a prominent activist in the field of life extension, published the book ‘The Life Extension Revolution’ and founded the nutraceutical (from ‘nutrition’ and ‘pharmaceutical’, in other words, a nutrition supplement) firm known as ‘The Life Extension Foundation’.

This foundation is a non-profit making organization promoting dietary supplements and publishing the periodical ‘Life Extension Magazine’. Kent was later involved in work relating to cryogenics. He was jailed in the course of this work over a dispute at one point, although charges were dropped at a later stage.

➢ In 1982, American health writer and life extension advocate Sandy Shaw and her co-writer, Durk Pearson, popularized the term ‘life extension’ even further with the bestseller ‘Life Extension: A Practical Scientific Approach’.

➢ Roy Walford, a gerontologist and life-extensionist, published ‘Maximum Lifespan’, another popular book on the subject. He and Richard Weindruch, his student, followed this up in 1988 with their summary on the research they had conducted into the ability to prolong the life of rodents through calorie restriction. The title of this book is ‘The Retardation of Aging and Disease by Dietary Restriction’.

Although this ability to extend life with calorie restriction had been known since the 1930’s, when gerontologist, biochemist and nutritionist Clive McCay did some research into the subject, it was the work of Walford and Weinbruch that gave solid scientific grounding to the McCay’s findings.

Walford’s scientific work was driven by a personal interest in life extension. He practiced calorie restriction as part of his own life and eventually died at the age of 80. The cause of his death was amyotrophic lateral sclerosis, a progressive motor neuron disease.

➢ A4M, the ‘American Academy of Anti-Aging Medicine’ was founded in 1992 to create a medical specialty for anti aging that was distinctly separate from geriatrics. This allowed scientists and physicians interested in this particular field of science to hold conferences and discuss the latest developments.

➢ The sci.life-extension, a Usenet group, was created by California-born author, philosopher and translator Brian M. Delaney. This represented an important development within the movement of life extension. It made it possible, for example, for the CR (Calorie Restriction) Society to be created.

➢ A more recent development is the proposal of Dr A. de Grey, a biogerontologist at Cambridge University. This proposal suggested that damage to cells, macromolecules, organs and tissues can be repaired with the help of advanced biotechnology. This is evident in hair restoration products, for instance.

More than Books

Although it would appear that most of the work revolving around life extension has been done solely by writing books or founding societies or organizations of some kind or another, the reality is that these books were written in response to or based on very specific, detailed scientific research that have yielded positive results.

They are no longer the works of hopeful minds, but the works of dedicated scientists who have spent their lives working on discovering facts about aging and trying to find ways to slow down, or even reverse the process.

Many breakthroughs have been made, and in many ways, we are already able to extend lives to a certain extent. The average lifespan of a human being is already far greater than it used to be as a result of medical, pharmaceutical and nutritional advances brought about by research and development.

The work continues, and scientists around the world are continually conducting research, comparing results, discussing options and making advances on our behalf.

Driving Forces behind the Development of the Life Extension Movement

What factors are driving this movement into ever greater efforts to find solutions to the extension of Life? The answer to this question actually includes a whole range of factors.

Expectations Have Risen

As the ‘baby boomer’ generation (born between 1946-1964) enters retirement age, expectations of this group are dramatically different from those of the preceding generations. They have greater expectations and desires to enjoy their life as pensioners to the fullest and for as long as is possible. This expectation covers not only length of life, but quality of life as well and this is not a passive request but an active and strident demand in many cases.

Pharmacology

Progress in pharmacology has led to a wide selection of drugs that allow people to live longer and fuller lives being developed over the last two decades or so. The work is still very much in progress and many more drugs are being developed daily.

One of the classic examples of a drug raising the quality of life for older individuals are erectile dysfunction treatments – notably Viagra, Cialis and Levitra. These drugs have dramatically reduced the number of fatalities or serious injury resulting from elderly men rolling out of bed, as well as a number of more qualitative benefits.

Advances in Genetics

Some of the latest scientific research and subsequent advances made in biotechnology and genetics are providing some hope that it may be possible to hold back some of the fundamental causes of aging.

As we outlined previously, chromosomes containing DNA strings are essentially capped with a binding substance known as telomeres. In effect, the telomeres are consumed during cell division and over time, they become shorter and shorter.

This was first observed by a scientist called Leonard Hayflick, and the process of limited cell division was subsequently named the Hayflick Limit. Advocates of life extension work on the thought that lengthening the telomeres through drugs or gene therapy may ultimately extend the Hayflick Limit and thereby fool the cells, and as such the body, into ‘thinking’ it is younger than it actually is.

Developments in Precision Manufacture

Advances made in the fields of nanotechnology, miniaturization, computer chips and robotics also provide hope for potentially life extending solutions.

In the 1970’s, a popular TV series starred Lee Majors as the ‘Six Million Dollar Man’? Science fiction then. Today, it is science fact. Millions of people now walk through life with artificial ankle, knee and hip joints and healthy feet. A generation ago, mass production of this kind of technology was a distant dream.

The same applies to many individuals with artificial limbs. Artificial legs used to be crude wooden contraptions that were just able to keep a person balanced. Today’s artificial limbs are almost fully functional.

The Blessings of Medical Progress

Who would have thought even 50 years ago that it would become possible to bypass a coronary artery, or even replace a heart completely? Yet there are hundreds of thousands, if not millions of individuals enjoying their lives after having this kind of surgery – few of whom would be alive just half a century ago.

Millions of people no longer have to wear glasses, because of the availability of laser surgery. This, too, was science fiction just a few years ago. Today, it is advertised next to shampoo in magazines and on TV.

In other words, science is moving rapidly towards not only extending life, but making the quality of these extra years better as well.

Is it Science, Science Fiction or Lunacy?

What should the average person believe? This question is almost as difficult to answer as finding solutions to extended life. Even among scientists, opinions are divided. Some do believe that extending the quality of life is as possible as extending life in general.

Others brush off the thought as un-scientific nonsense. This is often simply based on the fear of anything ‘new’ disturbing the status quo of established limits. Fortunately, real scientists do keep on looking, because if every single scientist had decided that some of the advancements already in medical, pharmaceutical and technological fields could not be possible, we would all still be dying at 30.

So where does that leave us?

There is no doubt what-so-ever that there are many charlatans out there trying to make a quick buck out of people’s desire to retain their youth. Even today, many products being sold in their millions are essentially non-effective – often given fantastic names and have the most bewildering ingredients to make them look scientific to consumers and justify their cost.

But the facts are while many advancements are being made and research points to the possibility of eventually finding the key to maintaining youth for longer, the scientific community is still warning the public that many of the products being sold today are unreliable to say the least.

➢ Although food supplements may assist in keeping a body healthier – something that can often be achieved by simply adopting a healthier life style and diet – there is as yet no categorical and undeniable proof that they slow down aging as such.

➢ The same goes for many hormone treatments. Although they may have a short term effect of some kind, it is not yet scientifically proven that they will actually work in the long run. The fear that it may not work is based on the fact that taking hormones, a good example is the hormonal acne treatment, will ultimately actually slow down the body’s own production of these hormones.

In addition, many treatments may have potential (and yet unknown) side effects in the long run that could be harmful to the user’s health. This includes the fears that such hormone treatments could increase the risk of cancer, diabetes and other major illnesses.

➢ Other ideas, like the calorie restriction method, are working for rodents. In fact, studies conducted with rats on 30 to 50 per cent restricted diets have shown to almost double the life span of rats.

Similar studies conducted on primates have also shown tendency to extend life to a certain extent and prevent a list of age related illnesses. There are as yet no studies on humans, although some are actually living on calorie restricted diets. Whether this will prolong their lives, however, is a question of having to wait and see.

The theory is that by reducing calorie intake, the metabolism of the body is slowed down, thereby slowing the aging process as well. Nutritionists say there is a certain amount of calories a body of a certain size and weight needs to have to maintain health. Reducing this amount by up to 50 per cent is hardly a good idea in the long term.

Time will tell, as they say, but how will anyone be able to tell the difference? If a person lives to the age of 80, is this because they are on this diet or would they have lived to this age anyway?

Where Will This Lead?

Many believe there is realistic hope and expectation of making significant strides in the area of longevity within the next two decades. This group typically believes the answer will ultimately lie within genetics and biotechnology. It is too early to make definite predictions, but the research so far shows promise and, as mentioned earlier, some of the results of this research are already being used in certain treatments to improve patients’ lives.

At present, overall aging is difficult to slow down, to say the least. Some products indicate they will assist in maintaining overall health/longevity, but the area we are seeing the first commercial products being developed is in the area of skin care and given the size of this market, it is likely that this will continue to be the weather-vane of longevity treatments.

Science or Snake Oil?

It will be difficult to tell these two apart for many years. Charlatans are likely to about, because it is difficult to disprove many theories easily. Equally difficult will be positive proof from those with an ethical perspective on the trail of a real breakthrough, as products based on valid research and using technology or ingredients that will actually have an effect rarely promise overnight results. This is something that anyone looking to find improved youthful looks, etc, will have to bear in mind. None of these products can perform miracles. Even the best of them will take time and regular use in order to achieve the desired effect.

The bottom line is that where we stand now, we can be sure there are some things which are ineffective or even harmful; there are some that show some promise and there are some that are starting to cross the line of being able to demonstrate results – albeit modestly at this point.

In the meantime, it is wise to research products very carefully and to refuse to be baffled by weird and wonderful sounding ingredients or fantastic sounding promises of instant youth. Regeneration will take time – let’s face it, it has taken a lifetime to get to this point, turning back the clock can never be possible over night.

Skin Care and the Life Extension Movement

One may well ask just what all this, and in particular the life extension movement as such, could possibly have to do with skin care, health and beauty products. The fact is, much of the research into life extension is resulting in new approaches to skin care as a kind of by-product.

A greater understanding of how genetics and cellular processes affect the aging and condition of skin allows these research and development teams to investigate different compounds, their compatibility with human cells and genetic make up.

Many compounds found in nature are not just compatible to human skin but in fact the skin cells actually have natural receptors for these compounds. Because life extension research has discovered these receptors, skin care developers can now use this knowledge and create the formulae for their products to provide maximum effect.

Another skin care ‘by-product’ of life extension research is the use of nanotechnology. The use of nanotechnology, or, to be more precise, nanoparticles, has had a huge impact on the way nutrients and other components of skin care products are being delivered to the skin cells. In some ways, nanotechnology has already revolutionized skin care. It is now possible to use active ingredients previously difficult to effectively deliver to the skin, as well as making old, proven ingredients even more effective. Some ingredients used in cosmetics for hundreds, if not thousands of years by certain cultures can now be even more effectively used to improve skin condition and maintain a healthy, youthful look.

Even the moisturizing effect of skin care products can be improved with nantechnology. For this effect, so-called nanosomes are used. Nanosomes are small, pocket-like particles that melt or disintegrate on skin contact. By doing this, the moisturising effect is accelerated, assisting the skin faster and more efficiently.

Nanotechnology plays a key part not only in slowing the aging of skin, but is believed to actively assist in repairing and healing skin cells and tissue.

Another breakthrough in life extension research that is beginning to make itself felt in skin care products is the research into stem cells. Stem cells are elements of all life, plant, animal and human. Stem cells have two properties other cells do not have. These properties are the ability to develop into any kind of cell type and the ability to divide almost indefinitely. The use of plant stem cell extracts in skin care is likely to become one of the next ‘big things’ in the industry. And prepare for the debate when human stem cells are proposed as part of an anti-aging skincare regime, as will inevitably occur!

One thing we can be certain of, is that science will continue to search for answers to the question of life extension, and business will drive the commercialization of discoveries. But whether these lead us to a utopian future or potentially a minefield of strife as we debate who will use and who will benefit from these new godlike powers. In the meantime, at a practical level in the skincare, health and beauty industry we remain hopeful and expectant we will see the emergence of products that not only promise results, but produce them.

David Christensen is a veteran of Asia Pacific business, currently residing in Bangkok, Thailand and heading up the business he was a co-founder of, Royal Siam Natural Health & Beauty – who can be located at [http://www.royalsiam.asia], and the information supporting site at [http://www.royalsiam.info]. Royal Siam was established after careful planning in early 2011, spending 2011 concentrating on building the necessary business infrastructure and concentrating on the domestic Thai market. Early in 2012 Royal Siam launched its international website and online store, and in April 2012 publicly declared the ambition to be among the world’s top 20 premium health and beauty brands by the year 2020. Royal Siam is a unique business, operating in the premium skincare, anti aging, and related fields. At its core, one mission is to commercialize and bring to a global market the immense wealth of knowledge about the healing and beneficial properties of Thai and South East Asian plants – a knowledge base carefully built up over the last thousand years. At the same time, the mission is to bring to market the very latest in scientific advances in the area of anti aging… resulting in the unique position of having a Thai heritage and offering the best of nature, tradition, and science.

Article Source: http://EzineArticles.com/expert/David_D_Christensen/1317312

Aging Is a Treatable Disease

May 22, 2016 by · Comments Off on Aging Is a Treatable Disease
Filed under: General 

Live Healthy – Look Marvelous – Live Longer

There are actions you can, and should take today to dramatically improve your health, your appearance and your longevity. You can control 70% of the factors affecting your longevity; only 30% are controlled by genetics until very late in life when genetics become more controlling

Almost all of the effects of aging and the common diseases that come with aging are treatable, to at least some extent. The key is early detection and early treatment.

Our understanding of the aging process is advancing rapidly. Some scientists believe that the first immortal human may be living today.

In 1786, life expectancy was 24 years. Better diets and some medical innovations allowed it to double to 48 years in the next 100 years.

Modern medicine has now increased life expectancy to over 76 years. Future medicine promises to increase it to over 100 years during our lifetime.

“Over half the baby boomers here in America are going to see their hundredth birthday and beyond in excellent health.” says Dr. Ronald Klatz of the American Academy of Anti-Aging. “We’re looking at life spans for the baby boomers and the generation after the baby boomers of 120 to 150 years of age.”

The key to Live Healthy – Look Marvelous – Live Longer is to delay the diseases of aging so that when they do occur, it is very late in your life.

The causes of aging are finally being understood. There are actions you can take today to take advantage of the recent medical developments. Dr. Rudman ran a series of tests on aging people and demonstrated that the effects of aging could be slowed and even reversed. He concluded: “The overall deterioration of the body that comes with growing old is not inevitable.”

The Causes of Aging

Almost all life on earth blossoms with youth, until it has reproduced and passed its genes on to the next generation. After that, the flowers wilt and die, and we humans began to age. Yes, we begin to age while we are still in our 20’s.

We age because the products of our metabolism, I.e., the “ashes” from the oxidation processes that produce energy in our cells, accumulate faster then our endocrine system can remove them. This is because most of the cleansing hormones that surged through our youthful bodies begin to decrease as we begin to age. Some of these more critical hormones have decreased by about 10 to 30% as we enter our 30’s. The decreases become ever more dramatic as we enter successive decades of life. Most of our hormones have decreased by over 50% and some have been reduced to near zero as we enter our 70’s. So we age. Our muscles and bones weaken; our reaction time slows; we lose our agility; all combine to make us more susceptible to accidents. Our immune system weakens and makes us more susceptible to disease. And we die.

The Death Clock

Dr. Hayflick has shown that we have another cause of aging. He has shown that we have a built-in death date of about 120 years, if diseases or accidents do not get us earlier. The point at which our cells have divided a fixed number of times sets this death date. It has been termed the “Hayflick limit.”

Our cells divide to produce new cells to replace the old cells damaged by metabolic ash build-up, free radicals, toxins, and other wear and tear mechanisms. As the cells divide, the chromosomes split to provide chromosomes for the new cells. When the chromosomes split, they lose part of their telomeres – the genes at their ends that keep the chromosomes organized. After a certain number of splits, the telomeres wear away and become too short to keep the chromosome organized and therefore the cell dies without being able to replace itself.

You can think of telomeres as analogous to the plastic bands on the ends of shoelaces. Telomeres hold the important DNA code intact, preventing it from fraying as the molecules replicate over time.

Resetting the Death Clock

But tests over the past few years have shown that the “Hayflick limit” can be extended by the use of an enzyme that causes the “organizing genes” at the ends of the chromosomes (the telomeres) to re-grow. This enzyme is called telomerase.

Telomerase treatments on human cells in the laboratory have indicated that telomerase can make human cells immortal. Doctors and researchers involved in these treatments are reporting that it is their belief that death is not inevitable.

Telomerase is actually an enzyme (a catalytic protein) that is able to arrest or reverse the telomere shortening process. The body produces telomerase when we are embryos in the womb to accommodate the very rapid growth of the embryo. But, unfortunately our bodies do not produce telomerase after birth except possibly for the creation of sperm.

So for humans to extend life we must do two things: first, eliminate the oxidants and toxins in our foods and environment; and find a dietary or pharmaceutical method for increasing and preserving the length of our cells’ telomeres.

Promising Anti-Aging Research

There are many ongoing projects that promise to solve our problems of aging. One is from a team of South Korean scientists. They report that they have created a newly-synthesized molecule, named CGK733 that can make cells younger.

“All cells face an inevitable death as they age. On this path, cells became lethargic and in the end stop dividing but we witnessed that CGK733 can block the process,” Prof. Kim Tae-kook reported. He further stated: “We also found the synthetic compound can reverse aging, by revitalizing already-lethargic cells. Theoretically, this can give youth to the elderly via rejuvenating cells.”

Kim expects that the CGK733-empowered drugs that keep cells youthful far beyond their normal life span would be commercialized in less than 10 years.

Researchers at The Wistar Institute have defined a key target of an evolutionarily conserved protein that regulates the process of aging. The study provides fundamental knowledge about key mechanisms of aging that could point toward new anti-aging strategies and cancer therapies.

Aging saps our strength and ability to enjoy life, cripples us, and eventually kills us. Tens of millions die from age-related conditions each and every year. Comparatively few people know that degenerative aging can be slowed with diet and lifestyle choices, medicines and nutracuetials.

Comparatively few people are aware of the many serious scientific efforts, presently underway, aimed at understanding and intervening in the aging process – in order to one day reverse its effects.

Your objective should be to have a healthy life and continue to live long enough to take advantage of all the medical advances and technologies now in development.

Our health is determined by our genetics, our diets, and our past and current lifestyles. You can now optimize your current and future health by defining and taking medications, vitamins, and other supplements and treatments tailored to your specific health needs. The program to do this recognizes the validity of three basic themes:

  • The Future of Medicine is in Personal Tailoring
  • Preventative Medicine is Key
  • Aging is a Treatable Disease.

Your Anti-Aging Longevity Plan

It is strongly recommended that you get familiar with the latest anti-aging information and develop your personal Longevity Plan. The key to longer life is to detect any health issues as early as possible and take advantage of the available technology to address them. Time really is of the essence.

Article Source: http://EzineArticles.com/5073181

The Programmed Cellular Death Approach to Anti-Aging Treatment

May 8, 2016 by · Comments Off on The Programmed Cellular Death Approach to Anti-Aging Treatment
Filed under: General 

Modern anti-aging treatment is built on a common base of knowledge that I will quickly review. Biochemistry and molecular biology tell us there are many types of chemical reactions going on in the human body. We know that it is the genetic information programmed inside our cellular DNA that defines what reactions occur. Genetic information, expressed in regulated ways, builds the body’s proteins and enzymes, and controls how enzymes carry out the cell’s biochemical reactions.

This information, contained in the DNA of our genome, consists of many thousands of long, often repetitive, sequences of base pairs that are built up from four basic nucleotides. Human genome mapping has shown there are over 3 billion base pairs in our DNA. It is estimated they contain some 20,000 protein-coding genes. All body functions are controlled by the expression of the genes in our genome. The mechanisms controlling the aging process are believed to be programmed into our DNA but only a fraction of the biochemical reactions related to the aging process have been looked at in any detail. Cellular aging is a very complex process and many of its low level operating details have yet to be discovered.

Anti-aging theory has consolidated itself along two lines of thought: the programmed cellular death theory and the cellular damages theory. The programmed death theory focuses on the root causes of aging. The cellular damages theory looks at the visible aspects of aging; i.e. the symptoms of aging. Both theories are correct and often overlap. Both theories are developing rapidly as anti-aging research uncovers more details. As works in progress these theories may take years to complete. This broad characterization also applies to the currently available types of anti-aging treatments.

The programmed death theory of aging suggests that biological aging is a programmed process controlled by many life span regulatory mechanisms. They manifest themselves through gene expression. Gene expression also controls body processes such as our body maintenance (hormones, homeostatic signaling etc.) and repair mechanisms. With increasing age the efficiency of all such regulation declines. Programmed cellular death researchers want to understand which regulatory mechanisms are directly related to aging, and how to affect or improve them. Many ideas are being pursued but one key area of focus is on slowing or stopping telomere shortening. This is considered to be a major cause of aging.

With the exception of the germ cells that produce ova and spermatozoa, most dividing human cell types can only divide about 50 to 80 times (also called the Hayflick limit or biological death clock). This is a direct consequence of all cell types having fixed length telomere chains at the ends of their chromosomes. This is true for all animal (Eukaryotic) cells. Telomeres play a vital role in cell division. In very young adults telomere chains are about 8,000 base pairs long. Each time a cell divides its telomere chain loses about 50 to 100 base pairs. Eventually this shortening process distorts the telomere chain’s shape and it becomes dysfunctional. Cell division is then no longer possible.

Telomerase, the enzyme that builds the fixed length telomere chains, is normally only active in young undifferentiated embryonic cells. Through the process of differentiation these cells eventually form the specialized cells from which of all our organs and tissues are made of. After a cell is specialized telomerase activity stops. Normal adult human tissues have little or no detectable telomerase activity. Why? A limited length telomere chain maintains chromosomal integrity. This preserves the species more than the individual.

During the first months of development embryonic cells organize into about 100 distinct specialized cell lines. Each cell line (and the organs they make up) has a different Hayflick limit. Some cell lines are more vulnerable to the effects of aging than others. In the heart and parts of the brain cell loss is not replenished. With advancing age such tissues start to fail. In other tissues damaged cells die off and are replaced by new cells that have shorter telomere chains. Cell division itself only causes about 20 telomere base pairs to be lost. The rest of the telomere shortening is believed to be due to free radical damage.

This limit on cell division is the reason why efficient cell repair can’t go on indefinitely. When we are 20 to 35 years of age our cells can renew themselves almost perfectly. One study found that at the age 20 the average length of telomere chains in white blood cells is about 7,500 base pairs. In humans, skeletal muscle telomere chain lengths remain more or less constant from the early twenties to mid seventies. By the age of 80 the average telomere length decreases to about 6,000 base pairs. Different studies have different estimates of how telomere length varies with age but the consensus is that between the age of 20 and 80 the length of the telomere chain decreases by 1000 to 1500 base pairs. Afterwards, as telomere lengths shorten even more, signs of severe aging begin to appear.

There are genetic variations in human telomerase. Long lived Ashkenazi Jews are said to have a more active form of telomerase and longer than normal telomere chains. Many other genetic differences (ex.: efficiency of DNA repair, antioxidant enzymes, and rates of free radical production) affect how quickly one ages. Statistics suggest that having shorter telomeres increases your chance of dying. People whose telomeres are 10% shorter than average, and people whose telomeres are 10% longer than average die at different rates. Those with the shorter telomeres die at a rate that is 1.4 greater than those with the longer telomeres.

Many advances in telomerase based anti-aging treatments have been documented. I only have room to mention a few of them.

– Telomerase has been used successfully to lengthen the life of certain mice by up to 24%.

– In humans, gene therapy using telomerase has been used to treat myocardial infarction and several other conditions.

– Telomerase related, mTERT, treatment has successfully rejuvenated many different cell lines.

In one particularly important example researchers using synthetic telomerase that encoded to a telomere-extending protein, have extended the telomere chain lengths of cultured human skin and muscle cells by up to 1000 base pairs. This is a 10%+ extension of telomere chain length. The treated cells then showed signs of being much younger than the untreated cells. After the treatments these cells behaved normally, losing a part of their telomere chain after each division.

The implications of successfully applying such techniques in humans are staggering. If telomere length is a primary cause of normal aging, then, using the telomere length numbers previously mentioned, it might be possible to double the healthy time period during which telomere chain lengths are constant; i.e. from the range of 23 to 74 years to an extended range of 23 to 120 or more years. Of course this is too optimistic because it is known that in vitro cultured cells are able to divide a larger number of times than cells in the human body but it is reasonable to expect some improvement (not 50 years but say 25 years).

We know that telomerase based treatments are not the final answer to anti-aging but there is no doubt that they can, by increasing the Hayflick limit, extend or even immortalize the lifespan of many cell types. It remains to be seen if this can be done safely done in humans.

Telomerase based treatments are only a partial answer to anti-aging. Please carefully research any anti-aging supplements based on this line of treatment. Through my articles and website I want to help you maintain your good health for the next 10 to 25 years. My hope is that within time period the fruits of anti-aging research will become available to everyone.

Article Source: http://EzineArticles.com/9227048

The Development of Old Age and Related Issues

April 18, 2016 by · Comments Off on The Development of Old Age and Related Issues
Filed under: General 

In traditional Chinese and other Asian cultures the aged were highly respected and cared for. The Igabo tribesmen of Eastern Nigeria value dependency in their aged and involve them in care of children and the administration of tribal affairs (Shelton, A. in Kalish R. Uni Michigan 1969).

In Eskimo culture the grandmother was pushed out into the ice-flow to die as soon as she became useless.

Western societies today usually resemble to some degree the Eskimo culture, only the “ice-flows” have names such a “Sunset Vista” and the like. Younger generations no longer assign status to the aged and their abandonment is always in danger of becoming the social norm.

There has been a tendency to remove the aged from their homes and put them  in custodial care. To some degree the government provides domiciliary care services to prevent or delay this, but the motivation probably has more to do with expense than humanity.

In Canada and some parts of the USA old people are being utilised as foster-grandparents in child care agencies.

SOME BASIC DEFINITIONS

What is Aging?

Aging: Aging is a natural phenomenon that refers to changes occurring throughout the life span and result in differences in structure and function between the youthful and elder generation.

Gerontology: Gerontology is the study of aging and includes science, psychology and sociology.

Geriatrics: A relatively new field of medicine specialising in the health problems of advanced age.

Social aging: Refers to the social habits and roles of individuals with respect to their culture and society. As social aging increases individual usually experience a decrease in meaningful social interactions.

Biological aging: Refers to the physical changes in the body systems during the later decades of life. It may begin long before the individual  reaches chronological age 65.

Cognitive aging: Refers to decreasing ability to assimilate new information and learn new behaviours and skills.

GENERAL PROBLEMS OF AGING

Eric Erikson (Youth and the life cycle. Children. 7:43-49 Mch/April 1960) developed an “ages and stages” theory of human development that involved 8 stages after birth each of which involved a basic dichotomy representing best case and worst case outcomes. Below are the dichotomies and their developmental relevance:

Prenatal stage – conception to birth.

  1. Infancy. Birth to 2 years – basic trust vs. basic distrust. Hope.
  2. Early childhood, 3 to 4 years – autonomy vs. self doubt/shame. Will.
  3. Play age, 5 to 8 years – initiative vs. guilt. Purpose.
  4. School age, 9to 12 – industry vs. inferiority. Competence.
  5. Adolescence, 13 to 19 – identity vs. identity confusion. Fidelity.
  6. Young adulthood – intimacy vs. isolation. Love.
  7. Adulthood, generativity vs. self absorption. Care.
  8. Mature age- Ego Integrity vs. Despair. Wisdom.

This stage of older adulthood, i.e. stage 8, begins about the time of retirement and continues throughout one’s life. Achieving ego integrity  is a sign of maturity while failing to reach this stage is an indication of poor development in prior stages through the life course.

Ego integrity: This means coming to accept one’s whole life and reflecting on it in a positive manner. According to Erikson, achieving integrity means fully accepting one’ self and coming to terms with death. Accepting responsibility for one’s life and being able to review the past with satisfaction is essential. The inability to do this leads to despair and the individual will begin to fear death. If a favourable balance is achieved during this stage, then wisdom is developed.

Psychological and personality aspects:

Aging has psychological implications. Next to dying our recognition that we are aging may be one of the most profound shocks we ever receive. Once we pass the invisible line of 65 our years are bench marked for the remainder of the game of life. We are no longer “mature age” we are instead classified as “old”, or “senior citizens”. How we cope with the changes we face and stresses of altered status depends on our basic personality. Here are 3 basic personality types that have been identified. It may be a oversimplification but it makes the point about personality effectively:

a. The autonomous – people who seem to have the resources for self-renewal. They may be dedicated to a goal or idea and committed to continuing productivity. This appears to protect them somewhat even against physiological aging.

b.The adjusted – people who are rigid and lacking in adaptability but are supported by their power, prestige or well structured routine. But if their situation changes drastically they become psychiatric casualties.

c.The anomic. These are people who do not have clear inner values or a protective life vision. Such people have been described as prematurely resigned and they may deteriorate rapidly.

Summary of stresses of old age.

a. Retirement and reduced income. Most people rely on work for self worth, identity and social interaction. Forced retirement can be demoralising.

b. Fear of invalidism and death. The increased probability of falling prey to illness from which there is no recovery is a continual source of anxiety. When one has a heart attack or stroke the stress becomes much worse.

Some persons face death with equanimity, often psychologically supported by a religion or philosophy. Others may welcome death as an end to suffering or insoluble problems and with little concern for life or human existence. Still others face impending death with suffering of great stress against which they have no ego defenses.

c. Isolation and loneliness. Older people face inevitable loss of loved ones, friends and contemporaries. The loss of a spouse whom one has depended on for companionship and moral support is particularly distressing. Children grow up, marry and become preoccupied or move away. Failing memory, visual and aural impairment may all work to make social interaction difficult. And if this then leads to a souring of outlook and rigidity of attitude then social interaction becomes further lessened and the individual may not even utilise the avenues for social activity that are still available.

d. Reduction in sexual function and physical attractiveness. Kinsey et al, in their Sexual behaviour in the human male, (Phil., Saunders, 1948) found that there is a gradual decrease in sexual activity with advancing age and that reasonably gratifying patterns of sexual activity can continue into extreme old age. The aging person also has to adapt to loss of sexual attractiveness in a society which puts extreme emphasis on sexual attractiveness. The adjustment in self image and self concept that are required can be very hard to make.

e. Forces tending to self devaluation. Often the experience of the older generation has little perceived relevance to the problems of the young and the older person becomes deprived of participation in decision making both in occupational and family settings. Many parents are seen as unwanted burdens and their children may secretly wish they would die so they can be free of the burden and experience some financial relief or benefit. Senior citizens may be pushed into the role of being an old person with all this implies in terms of self devaluation.

4 Major Categories of Problems or Needs:

Health.

Housing.

Income maintenance.

Interpersonal relations.

BIOLOGICAL CHANGES

Physiological Changes: Catabolism (the breakdown of protoplasm) overtakes anabolism (the build-up of protoplasm). All body systems are affected and repair systems become slowed. The aging process occurs at different rates in different individuals.

Physical appearance and other changes:

Loss of subcutaneous fat and less elastic skin gives rise to wrinkled appearance, sagging and loss of smoothness of body contours. Joints stiffen and become painful and range of joint movement becomes restricted, general mobility lessened.

Respiratory changes:

Increase of fibrous tissue in chest walls and lungs leads restricts respiratory movement and less oxygen is consumed. Older people more likelyto have lower respiratory infections whereas young people have upper respiratory infections.

Nutritive changes:

Tooth decay and loss of teeth can detract from ease and enjoyment in eating. Atrophy of the taste buds means food is inclined to be tasteless and this should be taken into account by carers. Digestive changes occur from lack of exercise (stimulating intestines) and decrease in digestive juice production. Constipation and indigestion are likely to follow as a result. Financial problems can lead to the elderly eating an excess of cheap carbohydrates rather than the more expensive protein and vegetable foods and this exacerbates the problem, leading to reduced vitamin intake and such problems as anemia and increased susceptibility to infection.

Adaptation to stress:

All of us face stress at all ages. Adaptation to stress requires the consumption of energy. The 3 main phases of stress are:

1. Initial alarm reaction. 2. Resistance. 3. Exhaustion

and if stress continues tissue damage or aging occurs. Older persons have had a lifetime of dealing with stresses. Energy reserves are depleted and the older person succumbs to stress earlier than the younger person. Stress is cumulative over a lifetime. Research results, including experiments with animals suggests that each stress leaves us more vulnerable to the next and that although we might think we’ve “bounced back” 100% in fact each stress leaves it scar. Further, stress is psycho-biological meaning the kind of stress is irrelevant. A physical stress may leave one more vulnerable to psychological stress and vice versa. Rest does not completely restore one after a stressor. Care workers need to be mindful of this and cognizant of the kinds of things that can produce stress for aged persons.

COGNITIVE CHANGE Habitual Behaviour:

Sigmund Freud noted that after the age of 50, treatment of neuroses via psychoanalysis was difficult because the opinions and reactions of older people were relatively fixed and hard to shift.

Over-learned behaviour: This is behaviour that has been learned so well and repeated so often that it has become automatic, like for example typing or running down stairs. Over-learned behaviour is hard to change. If one has lived a long time one is likely to have fixed opinions and ritualised behaviour patterns or habits.

Compulsive behaviour: Habits and attitudes that have been learned in the course of finding ways to overcome frustration and difficulty are very hard to break. Tension reducing habits such as nail biting, incessant humming, smoking or drinking alcohol are especially hard to change at any age and particularly hard for persons who have been practising them over a life time.

The psychology of over-learned and compulsive behaviours has severe implications for older persons who find they have to live in what for them is a new and alien environment with new rules and power relations.

Information acquisition:

Older people have a continual background of neural noise making it more difficult for them to sort out and interpret complex sensory input. In talking to an older person one should turn off the TV, eliminate as many noises and distractions as possible, talk slowly and relate to one message or idea at a time.

Memories from the distant past are stronger than more recent memories. New memories are the first to fade and last to return.

Time patterns also can get mixed – old and new may get mixed.

Intelligence.

Intelligence reaches a peak and can stay high with little deterioration if there is no neurological damage. People who have unusually high intelligence to begin with seem to suffer the least decline. Education and stimulation also seem to play a role in maintaining intelligence.

Intellectual impairment. Two diseases of old age causing cognitive decline are Alzheimer’s syndrome and Pick’s syndrome. In Pick’s syndrome there is inability to concentrate and learn and also affective responses are impaired.

Degenerative Diseases: Slow progressive physical degeneration of cells in the nervous system. Genetics appear to be an important factor. Usually start after age 40 (but can occur as early as 20s).

ALZHEIMER’S DISEASE Degeneration of all areas of cortex but particularly frontal and temporal lobes. The affected cells actually die. Early symptoms resemble neurotic disorders: Anxiety, depression, restlessness sleep difficulties.

Progressive deterioration of all intellectual faculties (memory deficiency being the most well known and obvious). Total mass of the brain decreases, ventricles become larger. No established treatment.

PICK’S DISEASE Rare degenerative disease. Similar to Alzheimer’s in terms of onset, symptomatology and possible genetic aetiology. However it affects circumscribed areas of the brain, particularly the frontal areas which leads to a loss of normal affect.

PARKINSON’S DISEASE Neuropathology: Loss of neurons in the basal ganglia.

Symptoms: Movement abnormalities: rhythmical alternating tremor of extremities, eyelids and tongue along with rigidity of the muscles and slowness of movement (akinesia).

It was once thought that Parkinson’s disease was not associated with intellectual deterioration, but it is now known that there is an association between global intellectual impairment and Parkinson’s where it occurs late in life.

The cells lost in Parkinson’s are associated with the neuro-chemical Dopamine and the motor symptoms of Parkinson’s are associated the dopamine deficiency. Treatment involves administration of dopamine precursor L-dopa which can alleviate symptoms including intellectual impairment. Research suggests it may possibly bring to the fore emotional effects in patients who have had psychiatric illness at some prior stage in their lives.

AFFECTIVE DOMAIN In old age our self concept gets its final revision. We make a final assessment of the value of our lives and our balance of success and failures.

How well a person adapts to old age may be predicated by how well the person adapted to earlier significant changes. If the person suffered an emotional crisis each time a significant change was needed then adaptation to the exigencies of old age may also be difficult. Factors such as economic security, geographic location and physical health are important to the adaptive process.

Need Fulfilment: For all of us, according to Maslow’s Hierarchy of Needs theory, we are not free to pursue the higher needs of self actualisation unless the basic needs are secured. When one considers that many, perhaps most, old people are living in poverty and continually concerned with basic survival needs, they are not likely to be happily satisfying needs related to prestige, achievement and beauty.

Maslow’s Hierarchy

Physiological

Safety

Belonging, love, identification

Esteem: Achievement, prestige, success, self respect

Self actualisation: Expressing one’s interests and talents to the full.

Note: Old people who have secured their basic needs may be motivated to work on tasks of the highest levels in the hierarchy – activities concerned with aesthetics, creativity and altruistic matters, as compensation for loss of sexual attractiveness and athleticism. Aged care workers fixated on getting old people to focus on social activities may only succeed in frustrating and irritating them if their basic survival concerns are not secured to their satisfaction.

DISENGAGEMENT

Social aging according to Cumming, E. and Henry, W. (Growing old: the aging process of disengagement, NY, Basic 1961) follows a well defined pattern:

  1. Change in role. Change in occupation and productivity. Possibly change in attitude to work.
  2. Loss of role, e.g. retirement or death of a husband.
  3. Reduced social interaction. With loss of role social interactions are diminished, eccentric adjustment can further reduce social interaction, damage to self concept, depression.
  4. Awareness of scarcity of remaining time. This produces further curtailment of activity in interest of saving time.

Havighurst, R. et al (in B. Neugarten (ed.) Middle age and aging, U. of Chicago, 1968) and others have suggested that disengagement is not an inevitable process. They believe the needs of the old are essentially the same as in middle age and the activities of middle age should be extended as long as possible. Havighurst points out the decrease in social interaction of the aged is often largely the result of society withdrawing from the individual as much as the reverse. To combat this he believes the individual must vigorously resist the limitations of his social world.

DEATH The fear of the dead amongst tribal societies is well established. Persons who had ministered to the dead were taboo and required observe various rituals including seclusion for varying periods of time. In some societies from South America to Australia it is taboo for certain persons to utter the name of the dead. Widows and widowers are expected to observe rituals in respect for the dead.

Widows in the Highlands of New Guinea around Goroka chop of one of their own fingers. The dead continue their existence as spirits and upsetting them can bring dire consequences.

Wahl, C in “The fear of death”, 1959 noted that the fear of death occurs as early as the 3rd year of life. When a child loses a pet or grandparent fears reside in the unspoken questions: Did I cause it? Will happen to you (parent) soon? Will this happen to me? The child in such situations needs to re-assure that the departure is not a censure, and that the parent is not likely to depart soon. Love, grief, guilt, anger are a mix of conflicting emotions that are experienced.

CONTEMPORARY ATTITUDES TO DEATH

Our culture places high value on youth, beauty, high status occupations, social class and anticipated future activities and achievement. Aging and dying are denied and avoided in this system. The death of each person reminds us of our own mortality.

The death of the elderly is less disturbing to members of Western society because the aged are not especially valued. Surveys have established that nurses for example attach more importance to saving a young life than an old life. In Western society there is a pattern of avoiding dealing with the aged and dying aged patient.

Stages of dying. Elisabeth Kubler Ross has specialised in working with dying patients and in her “On death and dying”, NY, Macmillan, 1969, summarised 5 stages in dying.

  1. Denial and isolation. “No, not me”.
  2. Anger. “I’ve lived a good life so why me?”
  3. Bargaining. Secret deals are struck with God. “If I can live until…I promise to…”
  4. Depression. (In general the greatest psychological problem of the aged is depression). Depression results from real and threatened loss.
  5. Acceptance of the inevitable.

Kubler Ross’s typology as set out above should, I believe be taken with a grain of salt and not slavishly accepted. Celebrated US Journalist David Rieff who was in June ’08 a guest of the Sydney writer’s festival in relation to his book, “Swimming in a sea of death: a son’s memoir” (Melbourne University Press) expressly denied the validity of the Kubler Ross typology in his Late Night Live interview (Australian ABC radio) with Philip Adams June 9th ’08. He said something to the effect that his mother had regarded her impending death as murder. My own experience with dying persons suggests that the human ego is extraordinarily resilient. I recall visiting a dying colleague in hospital just days before his death. He said, “I’m dying, I don’t like it but there’s nothing I can do about it”, and then went on to chortle about how senior academics at an Adelaide university had told him they were submitting his name for a the Order of Australia (the new “Knighthood” replacement in Australia). Falling in and out of lucid thought with an oxygen tube in his nostrils he was nevertheless still highly interested in the “vain glories of the world”. This observation to me seemed consistent with Rieff’s negative assessment of Kubler Ross’s theories.

THE AGED IN RELATION TO YOUNGER PEOPLE

The aged share with the young the same needs: However, the aged often have fewer or weaker resources to meet those needs. Their need for social interaction may be ignored by family and care workers.

Family should make time to visit their aged members and invite them to their homes. The aged like to visit children and relate to them through games and stories.

Meaningful relationships can be developed via foster-grandparent programs. Some aged are not aware of their income and health entitlements. Family and friends should take the time to explain these. Some aged are too proud to access their entitlements and this problem should be addressed in a kindly way where it occurs.

It is best that the aged be allowed as much choice as possible in matters related to living arrangements, social life and lifestyle.

Communities serving the aged need to provide for the aged via such things as lower curbing, and ramps.

Carers need to examine their own attitude to aging and dying. Denial in the carer is detected by the aged person and it can inhibit the aged person from expressing negative feelings – fear, anger. If the person can express these feelings to someone then that person is less likely to die with a sense of isolation and bitterness.

A METAPHYSICAL PERSPECTIVE

The following notes are my interpretation of a Dr. Depak Chopra lecture entitled, “The New Physics of Healing” which he presented to the 13th Scientific Conference of the American Holistic Medical Association. Dr. Depak Chopra is an endocrinologist and a former Chief of Staff of New England Hospital, Massachusetts. I am deliberately omitting the detail of his explanations of the more abstract, ephemeral and controversial ideas.

Original material from 735 Walnut Street, Boulder, Colorado 83002,

Phone. +303 449 6229.

In the lecture Dr. Chopra presents a model of the universe and of all organisms as structures of interacting centres of electromagnetic energy linked to each other in such a way that anything affecting one part of a system or structure has ramifications throughout the entire structure. This model becomes an analogue not only for what happens within the structure or organism itself, but between the organism and both its physical and social environments. In other words there is a correlation between psychological conditions, health and the aging process. Dr. Chopra in his lecture reconciles ancient Vedic (Hindu) philosophy with modern psychology and quantum physics.

Premature Precognitive Commitment: Dr. Chopra invokes experiments that have shown that flies kept for a long time in a jar do not quickly leave the jar when the top is taken off. Instead they accept the jar as the limit of their universe. He also points out that in India baby elephants are often kept tethered to a small twig or sapling. In adulthood when the elephant is capable of pulling over a medium sized tree it can still be successfully tethered to a twig! As another example he points to experiments in which fish are bred on

2 sides of a fish tank containing a divider between the 2 sides. When the divider is removed the fish are slow to learn that they can now swim throughout the whole tank but rather stay in the section that they accept as their universe. Other experiments have demonstrated that kittens brought up in an environment of vertical stripes and structures, when released in adulthood keep bumping into anything aligned horizontally as if they were unable to see anything that is horizontal. Conversely kittens brought up in an environment of horizontal stripes when released bump into vertical structures, apparently unable to see them.

The whole point of the above experiments is that they demonstrate Premature Precognitive Commitment. The lesson to be learned is that our sensory apparatus develops as a result of initial experience and how we’ve been taught to interpret it.

What is the real look of the world? It doesn’t exist. The way the world looks to us is determined by the sensory receptors we have and our interpretation of that look is determined by our premature precognitive commitments. Dr Chopra makes the point that less than a billionth of the available stimuli make it into our nervous systems. Most of it is screened, and what gets through to us is whatever we are expecting to find on the basis of our precognitive commitments.

Dr. Chopra also discusses the diseases that are actually caused by mainstream medical interventions, but this material gets too far away from my central intention. Dr. Chopra discusses in lay terms the physics of matter, energy and time by way of establishing the wider context of our existence. He makes the point that our bodies including the bodies of plants are mirrors of cosmic rhythms and exhibit changes correlating even with the tides.

Dr. Chopra cites the experiments of Dr. Herbert Spencer of the US National Institute of Health. He injected mice with Poly-IC, an immuno-stimulant while making the mice repeatedly smell camphor. After the effect of the Poly-IC had worn off he again exposed the mice to the camphor smell. The smell of camphor had the effect of causing the mice’s immune system to automatically strengthen as if they had been injected with the stimulant. He then took another batch of mice and injected them with cyclophosphamide which tends to destroy the immune system while exposing them to the smell of camphor. Later after being returned to normal just the smell of camphor was enough to cause destruction of their immune system. Dr. Chopra points out that whether or not camphor enhanced or destroyed the mice’s immune system was entirely determined by an interpretation of the meaning of the smell of camphor. The interpretation is not just in the brain but in each cell of the organism. We are bound to our imagination and our early experiences.

Chopra cites a study by the Massachusetts Dept of Health Education and Welfare into risk factors for heart disease – family history, cholesterol etc. The 2 most important risk factors were found to be psychological measures – Self  Happiness Rating and Job Satisfaction. They found most people died of heart disease on a Monday!

Chopra says that for every feeling there is a molecule. If you are experiencing tranquillity your body will be producing natural valium. Chemical changes in the brain are reflected by changes in other cells including blood cells. The brain produces neuropeptides and brain structures are chemically tuned to these neuropeptide receptors. Neuropeptides (neurotransmitters) are the chemical concommitants of thought. Chopra points out the white blood cells (a part of the immune system) have neuropeptide receptors and are “eavesdropping” on our thinking. Conversely the immune system produces its own neuropeptides which can influence the nervous system. He goes on to say that cells in all parts of the body including heart and kidneys for example also produce neuropeptides and neuropeptide sensitivity. Chopra assures us that most neurologists would agree that the nervous system and the immune system are parallel systems.

Other studies in physiology: The blood interlukin-2 levels of medical students decreased as exam time neared and their interlukin receptor capacities also lowered. Chopra says if we are having fun to the point of exhilaration our natural interlukin-2 levels become higher. Interlukin-2 is a powerful and very expensive anti-cancer drug. The body is a printout of consciousness. If we could change the way we look at our bodies at a genuine, profound level then our bodies would actually change.

On the subject of “time” Chopra cites Sir Thomas Gall and Steven Hawkins, stating that our description of the universe as having a past, present, and future are constructed entirely out of our interpretation of change. But in reality linear time doesn’t exist.

Chopra explains the work of Alexander Leaf a former Harvard Professor of Preventative Medicine who toured the world investigating societies where people  lived beyond 100 years (these included parts of Afghanistan, Soviet Georgia, Southern Andes). He looked at possible factors including climate, genetics, and diet. Leaf concluded the most important factor was the collective perception of aging in these societies.

Amongst the Tama Humara of the Southern Andes there was a collective belief that the older you got the more physically able you got. They had a tradition of running and the older one became then generally the better at running one got. The best runner was aged 60. Lung capacity and other measures actually improved with age. People were healthy until well into their 100s and died in their sleep. Chopra remarks that things have changed since the introduction of Budweiser (beer) and TV.

[DISCUSSION: How might TV be a factor in changing the former ideal state of things?]

Chopra refers to Dr. Ellen Langor a former Harvard Psychology professor’s work. Langor advertised for 100 volunteers aged over 70 years. She took them to a Monastery outside Boston to play “Let’s Pretend”. They were divided into 2 groups each of which resided in a different part of the building. One group, the control group spent several days talking about the 1950s. The other group, the experimental group had to live as if in the year 1959 and talk about it in the present tense. What appeared on their TV screens were the old newscasts and movies. They read old newspapers and magazines of the period. After 3 days everyone was photographed and the photographs judged by independent judges who knew nothing of the nature of the experiment. The experimental group seemed to have gotten younger in appearance. Langor then arranged for them to be tested for 100 physiological parameters of aging which included of course blood pressure, near point vision and DHEA levels. After 10 days of living as if in 1959 all parameters had reversed by the equivalent of at least 20 years.

Chopra concludes from Langor’s experiment: “We are the metabolic end product of our sensory experiences. How we interpret them depends on the collective mindset which influences individual biological entropy and aging.”

Can one escape the current collective mindset and reap the benefits in longevity and health? Langor says, society won’t let you escape. There are too many reminders of how most people think linear time is and how it expresses itself in entropy and aging – men are naughty at 40 and on social welfare at 55, women reach menopause at 40 etc. We get to see so many other people aging and dying that it sets the pattern that we follow.

Chopra concludes we are the metabolic product of our sensory experience and our interpretation gets structured in our biology itself. Real change comes from change in the collective consciousness – otherwise it cannot occur within the individual.

Readings

Chopra, D. The New Physics of Healing. 735 Walnut Street, Boulder, Colorado 83002,

Phone. +303 449 6229.

Coleman, J. C. Abnormal psychology and modern life. Scott Foresman & Co.

Lugo, J. and Hershey, L. Human development a multidisciplinary approach to the psychology of individual growth, NY, Macmillan.

Dennis. Psychology of human behaviour for nurses. Lond. W. B.Saunders.

[http://www.psychologynatural.com/DepressionBroch.html]

Dr. Victor Barnes is an Adelaide psychologist and hypnotherapist. He has also had three decades of experience in adult education including serving as Dean of a Sri Lankan college (ICBT) teaching several Australian degrees. His overseas experience includes studies and consulting experience in USA, PNG, Poland and Sri Lanka.

Life Insurance Planning for Senior Citizens by Natalie Aranda

May 31, 2013 by · Leave a Comment
Filed under: Articles 

Life Insurance has sometimes been described as a bet between you and the Insurance Company. The Insurance Company is betting that you are going to live and you are betting that you are going to die. If you do die, you win the bet. This approach has been the basis of life Insurance policies in the past. Despite the fact that it would seem this does not much benefit an individual, the truth was that the Life Insurance payout was designed to provide for those that you left behind.

Changes in health care and the increasing life span have brought some changes to this concept. The desire for senior citizens to spend their retirement in an active adult community where they can enjoy their golden years to the maximum has prompted many to take a fresh approach to the use of the cash value of life insurance. It has also influenced the type of policies that have become popular. When a payout upon death was the main purpose of an insurance policy, the only thing that mattered was the amount of the death benefit.

Today, people in increasing numbers are opting to not spend their last years in their homes. An Arizona active adult community that is located in an area without a harsh winter seems much more attractive. A Florida active adult community situated close to the ocean would be preferably to long cold winters. This is the new dream of senior citizens, but in many cases the funds needed to make this dream come true are not available at the time of retirement. It has become possible to redeem the cash value of an insurance policy prior to death through an annuity settlement. The basic idea is the seller of the annuity provides a cash settlement to you at retirement. In return, they basically become the new beneficiary of your policy.

The annuity settlement changes the conditions of the bet. Now, you are betting that you are going to live, and the new beneficiary of your policy is betting you will die. If you live, you win. Many senior citizens are seeing this as a better idea. It takes some careful planning, and each case must be considered individually. The debt situation and the situation of a spouse and of children must be taken into consideration. The increased popularity of Individual Retirement Accounts has lessened the need for a large death payout to some degree. The best time to plan for your life insurance needs as a senior citizen is long before you ever become one. Sadly, this is not always done until too late. In this case, the options can be considered. It is not a time to be rash and seeking the advice of a trusted Insurance agent or financial advisor is highly recommended. If you plan on spending your last years enjoying a California active adult community, start that planning as early as possible.

Natalie Aranda writes about finance. Today, people in increasing numbers are opting to not spend their last years in their homes. An Arizona active adult community that is located in an area without a harsh winter seems much more attractive. A Florida active adult community situated close to the ocean would be preferably to long cold winters. This is the new dream of senior citizens, but in many cases the funds needed to make this dream come true are not available at the time of retirement.

Article Source: http://EzineArticles.com/?expert=Natalie_Aranda

Cleveland Clinic September calendar of social services and education programs

September 1, 2012 by · Leave a Comment
Filed under: Events, General 

September calendar of social services and education programs for individuals, caregivers and family members impacted by brain diseases. All of these programs are open to the community and offered free of charge.

Healthy Aging: Up2Me – New Session Begins on September 28, 12:30 pm – 3:00 pm
Join us for this proven six week program helping caregivers and individuals with chronic diseases set goals and develop skills for success. Free and open to the public, advance registration required. Contact Susan, 483-6023, hirschs2@ccf.org

Lunch & Learn
Wednesdays, 12 noon – 1 pm
888 W. Bonneville Avenue, Las Vegas
Bring your lunch, drink & dessert provided; open to the public

Sept 5: What You Need to Know Before a Hospital Stay, Rose O’Donnell-Barker, RN BSN, Valley Hospital Medical Center
A hospital stay can be stressful for anyone. For those with Alzheimer’s or other memory disorders, being in an unfamiliar environment presents unique challenges. Learn strategies to address issues that can arise for patients and caregivers during a hospital stay.

September 12: Understanding Grief & Loss, Esther Langston, PhD, Professor Emeritus, UNLV School of Social Work
This presentation will explore grief and loss over the life span and increase our understanding of how we are affected as individuals and caregivers.

Sept 19: Tea Time & Spices of Life, Kristopher Hightower, Keep Memory Alive Café
A conversation about teas and spices of the world and their benefits. Tasting and samples!

Sept 26: Special Social Service Programs: CarePRO & Health Aging: Up2Me, Susan Solorzano, Pam Fine & Patti Nixon
Join us for this presentation on two special social service programs which have been proven to be effective: 1) CarePRO which provides education and support for dementia caregivers and 2) Healthy Aging: Up2Me, a 6 week program helping caregivers and individuals with chronic illness to set goals and develop skills for success.

Cleveland Museum of Art Series
Dynamic conversations about art through videoconferencing
All art education programs are held at the Lou Ruvo Center for Brain Health Library, 888 W. Bonneville Avenue and open to the public.

Ancient American Art: The Aztec and their Ancestors
September 4, 11:00 am – 12:00 noon
Learn about the art of selected cultures in ancient Mesoamerica. Ceramic, gold and stone objects will be examined to shed light on religion and rulership among the Aztec, Maya and other cultures.

Self Portraits
September 18, 11:00 am – 12:00 noon
Our self image influences many elements including our perspective, decision-making and daily experiences. We will explore ways in which artists from Rembrandt to Picasso represent themselves through their personal statements, historical moments and other approaches.

Contact Susan Hirsch, 483-6023 or hirschs2@ccf.org for additional information.
Support Groups
MEMORY LOSS SUPPORT GROUP
Wednesdays, 1 pm-2:30 pm
Meetings are held weekly for adult members who provide care for loved ones with memory loss.
Contact: Donna Munic-Miller 483-6035, municd@ccf.org
PARKINSON’S DISEASE SUPPORT GROUP: September 11, 12 noon -1 pm
(Held the 2nd Tuesday of every month)
Christopher Borsellino, MA Ed of Deaf, MS/CCC-SLP from Speech Logic is guest speaker. Early stage group and adult family members meet together in the Library.
Contact: Jennifer 483-6036, gayanj@ccf.org

HUNTINGTON’S DISEASE SUPPORT GROUP: September 25, 12 noon -1 pm
(Held the 4th Tuesday of every month)
Separate groups for gene positive individuals (asymptomatic and early stage) and adult family members.
Contact: Jenna 483-6054, clifforj@ccf.org

  • Senior Industry Network Group Events

    Monthly SING Meetings are held the first Thursday of every month at our NEW location below:

    Desert Canyon - HealthSouth
    9175 W. Oquendo Rd.
    Las Vegas, NV 89148

    S.I.N.G. Agenda:
    - Coffee and bagels will be served
    - A time to show gratitude by thanking those who have sent you referrals
    - Announcements around the room
    - One minute commercials
    - Open Discussion on topics of Self Empowerment

    * When? The 1st Thursday of every month. Networking starts at: 8:00am | Meeting starts at: 8:30am

    * How Much? It’s free!